منابع مشابه
Is hypertension an autoimmune disease?
T cells are required for significant blood pressure elevation in mouse models of hypertension. Recent evidence suggests that the treatments that raise blood pressure in these animal models also cause oxidation within DCs, resulting in formation of isoketal adducts of self-proteins, which activate antigen-presenting functions of these cells and serve as a source of modified self-antigens. T cell...
متن کاملIdiopathic portal hypertension associated with autoimmune thyroiditis.
We report a case of idiopathic portal hypertension (IPH) in association with autoimmune thyroiditis occurring in a 39 year old woman. Ultrasonography revealed a normal liver echotexture. Spleno-portogram confirmed portal hypertension and liver biopsy showed features in keeping with IPH. She was also found to be biochemically hypothyroid with markedly elevated thyroid autoantibodies. These findi...
متن کاملAutoimmune disease and unexplained pulmonary hypertension.
T he article by Barst et all provides new and important information related to the association of unexplained pulmonary hypertension in children with the major histocompatibility complex (MHC) and has opened up a new dimension of investigation. There is good rationale for immune mediation of pulmonary hypertension as detailed in the article, given the presence of this condition in patients with...
متن کاملThalassemia Associated Pulmonary Hypertension
Cardiac disease is the main cause of death in both forms of thalassemia; thalassemia major (TM) and thalassemia intermedia (TI). Pulmonary hypertension (PH) is one of the cardiopulmonary morbidities with high mortality that, if not treated, may trigger right-sided heart failure and premature death. PH is defined as a mean pulmonary artery pressure of ≥25 mmHg at rest or ≥30 mmHg during exercise...
متن کاملPulmonary arterial hypertension: an autoimmune disease?
P ulmonary arterial hypertension (PAH) is a rare condition that occurs as a consequence of chronic obstruction of small pulmonary arteries due to endothelial cell, vascular smooth muscle cell and fibroblast dysfunction and proliferation [1]. In recent years, major advances have been achieved in the understanding of PAH pathophysiology [1–7]. It has been firmly demonstrated that pulmonary artery...
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ژورنال
عنوان ژورنال: Current Hypertension Reports
سال: 2019
ISSN: 1522-6417,1534-3111
DOI: 10.1007/s11906-019-0914-2